Notre Dame vs. Louisville,
09/02/2019 20:00 EDT,
Score: 35 - 17
Point Spread: -18/-106 Notre Dame
Notre Dame is the much better team all-around, better QB, Better Offense, Better defense. Louisville was just 1-11 ATS last year. With a couple of tougher matchups coming up ahead this year, Notre Dame needs to capitalize on these weaker opponents. Louisville was just 1-11 ATS last year and just added more inexperienced rookies to their horrible defense. I expect them to struggle in their 1st college game. Let's lay the big number with Notre Dame as I expect them to win this by at least 3 touchdowns.